KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC6
All Species:
29.39
Human Site:
T228
Identified Species:
49.74
UniProt:
Q99741
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99741
NP_001245.1
560
62720
T228
K
E
L
K
G
F
K
T
I
M
L
N
C
M
S
Chimpanzee
Pan troglodytes
XP_001170406
560
62717
T228
K
E
L
K
G
F
K
T
I
M
L
N
C
M
S
Rhesus Macaque
Macaca mulatta
XP_001096756
559
62520
T228
K
E
L
K
G
F
K
T
I
M
L
N
C
M
S
Dog
Lupus familis
XP_537648
559
62507
T227
K
E
L
K
D
F
K
T
I
M
L
N
C
M
S
Cat
Felis silvestris
Mouse
Mus musculus
O89033
562
62595
S230
K
E
V
K
G
F
K
S
I
L
L
N
C
M
S
Rat
Rattus norvegicus
NP_001101768
561
62295
T229
K
E
V
K
G
F
K
T
I
V
L
N
C
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519126
361
39672
Q67
R
R
L
V
F
E
D
Q
L
A
S
R
S
P
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081844
554
60731
T222
D
D
L
K
Q
C
K
T
V
Y
I
N
C
M
S
Zebra Danio
Brachydanio rerio
NP_001120805
561
61262
T244
A
L
L
K
G
I
Q
T
V
V
I
N
C
M
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648247
662
75116
V323
F
S
K
R
L
Q
R
V
Y
I
N
C
T
S
I
Honey Bee
Apis mellifera
XP_625142
549
62089
I221
F
K
S
K
F
N
I
I
Y
I
N
C
T
T
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999666
582
64455
H221
S
S
R
R
N
T
Q
H
I
F
V
N
C
M
L
Poplar Tree
Populus trichocarpa
XP_002299817
498
55546
P204
K
V
M
E
K
N
Q
P
G
K
K
I
N
G
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09119
513
58018
F218
P
Y
H
K
K
T
T
F
V
V
V
L
D
E
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96
89.1
N.A.
79.5
80
N.A.
45.3
N.A.
63.7
49
N.A.
33.9
36
N.A.
40
Protein Similarity:
100
100
97.5
93.5
N.A.
87.3
88.9
N.A.
52.8
N.A.
77.5
67.3
N.A.
52.1
57.3
N.A.
58.5
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
6.6
N.A.
53.3
46.6
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
20
N.A.
73.3
80
N.A.
20
20
N.A.
46.6
Percent
Protein Identity:
25.8
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
46.4
N.A.
N.A.
N.A.
41.2
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
15
65
0
0
% C
% Asp:
8
8
0
0
8
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
43
0
8
0
8
0
0
0
0
0
0
0
8
0
% E
% Phe:
15
0
0
0
15
43
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
43
0
0
0
8
0
0
0
0
8
8
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
8
8
50
15
15
8
0
0
8
% I
% Lys:
50
8
8
72
15
0
50
0
0
8
8
0
0
0
0
% K
% Leu:
0
8
50
0
8
0
0
0
8
8
43
8
0
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
29
0
0
0
65
15
% M
% Asn:
0
0
0
0
8
15
0
0
0
0
15
65
8
0
8
% N
% Pro:
8
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
8
22
8
0
0
0
0
0
0
0
% Q
% Arg:
8
8
8
15
0
0
8
0
0
0
0
8
0
0
0
% R
% Ser:
8
15
8
0
0
0
0
8
0
0
8
0
8
8
58
% S
% Thr:
0
0
0
0
0
15
8
50
0
0
0
0
15
8
0
% T
% Val:
0
8
15
8
0
0
0
8
22
22
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
15
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _